What are Tramadol and Vicodin? Tramadol and Vicodin (hydrocodone/ acetaminophen) are potent pain relievers that can be used when OTC medications do not provide sufficient pain relief. They are often prescribed for short-term use following medical surgeries or injuries. You can buy Vicodin online overnight to relieve your post-surgery pain. Tramadol Tramadol drug was patented
Oxycontin vs Vicodin Oxycontin and Vicodin are both prescription painkillers. They are both opioids, which means they work by binding to opioid receptors in the brain to decrease pain perception. Oxycontin is a time-release formulation, which means it is designed to release the medication slowly. Vicodin combines acetaminophen (a pain reliever) and hydrocodone (an opioid).