Difference between Oxycodone and Hydrocodone

Difference between Oxycodone and Hydrocodone


Oxycodone, also known as Percocet, is an opioid or narcotic pain reliever that works on the CNS (central nervous system) to relieve pain. Oxycodone is made by modifying thebaine, an organic chemical found in opium. Oxycodone, also known as a semi-synthetic opiate, acts by blocking pain signals that travel from our body along nerves to the brain.

The Oxycodone effects commonly start within 30-60 minutes after the usage. Depending on the dosage, these effects may stay between four and six hours. You may buy Oxycodone online from your nearby pharmacy store to alleviate the pain.


Hydrocodone is also a semi-synthetic opiate or pain reliever mainly prescribed to treat moderate to severe pain in the body. Hydrocodone, also known as Vicodin, is commonly prescribed as a short-term option after surgery or to treat and alleviate injury-related pain.

Oxycodone and Hydrocodone are highly prescribed and most effective medicines for treating pain. You are most welcome if you want to buy Hydrocodone online from our partner pharmacy store.

What’s the main difference between Oxycodone & Hydrocodone?

This is very technical, but the critical difference between Oxycodone and Hydrocodone is that Oxycodone has an extra oxygen atom. Also, Oxycodone is synthesized from thebaine and is used only for pain relief, whereas Hydrocodone is derived from codeine and might be used to relieve coughs and pain.

Like Oxycodone, drug manufacturers often mix Hydrocodone with acetaminophen & other substances to make powerful & effective pain relievers. Oxycodone and Hydrocodone; are the most popular prescribed drugs in the USA.

hydrocodone and oxycodone

How can you take them?

A person should always take Oxycodone and Hydrocodone according to the prescription of their pharmacist or health care provider. These drugs are obtainable in various forms, such as:

  • concentrated liquids
  • liquids
  • extended-release tablets
  • extended-release capsules

Both these medications are also obtainable in combination with other pain relievers, such as:

  • aspirin
  • acetaminophen
  • ibuprofen

A person takes an ER (extended-release) Oxycodone every 12 hours with food. In contrast, they may commonly take an extended-release Hydrocodone once daily, at about the same time every day. Before taking it, you shouldn’t crush, chew, soak, or tamper with an extended-release tablet. It is essential to follow the guidelines and instructions of your healthcare provider when you stop taking opioid medicine.

These drugs are highly addictive or habit-forming; discontinuing them abruptly may result in withdrawal symptoms. You may buy Hydrocodone online from the store mentioned above to get up to a 10% instant discount with proper details and flexible overnight delivery. They are one of the best and most trustworthy pharmacy stores in the USA, offering free consultancy services, including Hydrocodone and Oxycodone. Besides, you may buy Oxycodone from the same place to relieve the pain. Hurry up! And purchase your drugs.

How effective are Oxycodone and Hydrocodone?

Oxycodone and Hydrocodone are potent pain relievers and be highly effective in treating pain. In the event of an emergency, experts found that these two drugs treat pain equally. In a study on both medicines, experts found that Hydrocodone and Oxycodone were similarly effective in treating pain caused due to fractures.

People experienced equal pain relief 30 and 60 minutes after the medicine was consumed. However, those who were given Hydrocodone experienced constipation more frequently than those who used Oxycodone. Another research found that the mixture of Oxycodone & acetaminophen was 1.5 times more potent than Hydrocodone with acetaminophen when taken at equal doses.

Both Hydrocodone and Oxycodone are effective in decreasing pain sensations. However, they may not address the underlying cause of the pain. Due to the risk of habit forming (addiction) and dependence, many experts recommend exploring other options for taking opioid pain medications.

What should I avoid while using Oxycodone and Hydrocodone?

It will help if you avoid drinking alcohol. Unwanted, dangerous side effects or death may happen. It would help if you avoided operating machinery or driving until you know how these drugs will impact your body. Severe drowsiness & dizziness may cause other accidents & falls. Users need to avoid medication errors. Keep tracking the brand & strength of Oxycodone and Hydrocodone you get from the pharmacy.

To avoid the reactions and symptoms, it’s essential to buy Oxycodone from a suitable place and take it under the supervision of an experienced healthcare expert. The same suggestions apply to Hydrocodone as well.

What are the side effects of Oxycodone and Hydrocodone?

As we know, these drugs are the most effective painkillers; but some people continuously misuse them and get unwanted negative impacts on their bodies. Here we will mention a few common side effects of Oxycodone and Hydrocodone.

Oxycodone and Hydrocodone both have many of the same side effects, such as:

  • Headache, dry mouth, dizziness
  • Vomiting & nausea
  • Stomach ache, dry mouth, hives

Oxycodone and Hydrocodone may cause similar severe side effects as well; such as:

  • Trouble breathing, seizures
  • Dizziness or weakness
  • Slow heartbeat, cold, clammy skin

Although these are not a complete list of side effects, if you don’t want these effects on your body, you may buy Oxycodone online Direct from the abovementioned store. There you may get proper instructions about the usage and dosing details of Oxycodone. If you buy this drug from that place, you may get it at an affordable rate. you may buy Oxycodone and Hydrocodone from there as well.

How much time or how long does Oxycodone stay in your body?

People using Oxycodone may wonder or Desire how long the drug will appear on a drug test. Oxycodone’s half-life is only a few hours, and the drug is completely cleared from the body within a day. Because of this, some people believe they can pass an oxycodone drug test one day after their last dose of Oxycodone.

However, what determines the duration that a drug test detects traces of medication has more to do with the metabolites of drugs (i.e., what the medication metabolizes into) than the drug’s half-life.

Oxycodone itself does not present in the body, but it can be metabolized into noroxycodol, or oxycodone, oxymorphone, oxymorphone, etc., and may remain even after the original form has disappeared. The metabolites appear more in specific components of the system than in others, resulting in various trace windows per test type.

Urine- Urinalysis reveals oxycodone use about 3 to 4 days after the last use. Oxycodone may first appear in the urine within hours of ingestion.

Hair- Oxycodone may be detectable in hair for about three months or 90 days after the last usage, but it takes almost a week to appear in an individual’s hair following the last use.

Blood- Oxycodone can be detectable in the blood for almost one day (24 hours) after the last usage. The drug is visible in the bloodstream within 15-30 minutes following the most recent use.

Saliva- A saliva test may reveal traces of Oxycodone for up to 4 days following the latest usage. Oxycodone can be detectable in saliva within 15 minutes of the latest use.

Other factors that may determine Oxycodone half-life include the urine’s pH, metabolic rate, & how frequently a person takes it. If you buy Oxycodone and use it often, it might take longer for it to be removed because it builds up in your system.

How much time or how long does Hydrocodone last in your system?

Hydrocodone has a half-life of just under 4 hours, meaning it takes that long to remove half of the dosage of the drug. It is metabolized in the liver & excreted through urine. Up to 20 percent of the dose is eliminated as Hydrocodone, with up to 14 percent excreted as hydrocodone & up to 6 percent as hydromorphone. Various factors are essential in determining exactly how long this medicine takes to be removed from the system.

Blood- It will take a day for Hydrocodone to clear the blood for most healthy people completely.

Urine- Hydrocodone passes via the urine, which might be detected for 2-4 days after the last dosage.

Saliva- The drug may be detectable in a saliva test for up to 36 hours after the last dosage.

Hair- Hydrocodone might be detectable much longer with a hair follicle drug test for up to 3 months (90 days).

You may buy Hydrocodone online for its long-lasting and effective analgesic or pain-relieving impacts.


Oxycodone and Hydrocodone are effective pain reliever medicines. They both relate to the drug class called narcotics or opioids. They both are pretty similar, and there are not so many huge differences among them. You may buy both Oxycodone and Hydrocodone online from the previously mentioned place since it is the best place to purchase any medicine online. They deliver genuine & superior-quality drugs.

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